One of the biggest usability problems you encounter in a fully Ajaxified site (i.e., a completely dynamic site that functions with little to no page refreshes)…is the fact that anything you load dynamically on the page without a refresh is blind to the browser’s buttons, as well as bookmarking.
On page load, something like RegEx could be used to parse the query
On another note, Smugmug has released a new version of their site that is proof positive that this technique can sucessfully be done. Well done! I’m really excited to start using this technique on our projects over at Blue Lava.